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Normal Unicode characters are 2‑byte long while Unicode Supplementary characters are 4‑byte long. Aspose.Cells for Python via .NET now supports rendering of these 4‑byte Unicode characters.
In the Unicode Character Standard, Supplementary Characters are the characters assigned code points from U+10000 to U+10FFFF. In other words, these are the Unicode characters greater than U+FFFF.
The following screenshot shows how Aspose.Cells for Python via .NET rendered the source Excel file into the output PDF. As you can see, all three Unicode Supplementary characters have been rendered exactly the same as those rendered by Microsoft Excel.

You can use this sample code to convert the source Excel file into the output PDF.
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